Our initial success with burns strongly suggested that the Cord Lining Stem Cells could also resurface chronic wounds and ulcers. The examples below show successful treatments we have achieved on ulcers and wounds where conventional treatments had failed. We hypothesised that the Cord Lining Stem Cells were secreting proteins that had modulated the chronic wound environment, making it amenable for repair.
Examples of successful treatments of wounds using our stem cell technology:
- 2 year old male with a chronic ulcer on the ankle after being treated for a blood vessel tumour, called a vascular malformation, with external irradiation. The vascular malformation shrank but a gaping wound was left in its wake. Treatment with Cord Lining Stem Cells closed the wound in 20 days after it had failed to heal for 3 months.
14-year-old male with a clotting disorder called Haemophilia. Patients with this condition are unable to clot their blood and can die from uncontrolled bleeding. In his history he bumped his ankle, which accumulated a blood clot (called a haematoma). This broke down revealing a large ulcer. His surgeons were unable to take a skin graft for fear he might bleed uncontrollably from where the skin graft was harvested (called the skin graft donor site). Treatment with Cord Lining Stem Cells healed the wound in 42 days without need for a skin graft.
30-year-old female who sustained severe injuries in a road traffic accident when she was flung from a motorcycle, sustaining arm fractures and tissue loss. Bone was exposed and skin grafting on bone was not feasible so her surgeons suggested amputation. Fearful of losing her forearm, this young lady opted to use Cord Lining Stem Cells, which successfully closed the wound over the exposed bone after 21 days, saving her from a forearm amputation.
CellResearch is actively conducting chronic wound resurfacing applications using Cord Lining Stem Cells with these clinical collaborators:
- Dr. Mai Manh Tuan at St Paul’s Hospital Burns Centre and the National Hospital of Traditional Medicine in Hanoi, Vietnam;
- Dr. Dinh Van Han at Hospital 103 in Hanoi, Vietnam