In-vitro cell research is at the heart of this division. Our capable team of scientists are happy to take on contract research for companies, research institutes and researchers. By obtaining dependable data and products from us, researchers need not lose sight of the other aspects of their projects, and yet be confident in getting the reliable project results they expect within the project time constraints.

In-vitro models for wound healing, skin biology research and drug discovery

Monolayer (2-D) primary skin cell culture (fibroblasts, keratinocytes, melanocytes)

3-D primary skin cell culture (fibroblast-populated collagen lattices, cultured full thickness epidermis)

Cell co-culture (for direct cell-cell interaction studies)

Double-chamber cell co-culture (for paracrine interaction studies)

Organotypic co-culture model (cultured skin equivalents)

Organ culture (explant techniques)

Applications: These models can be used to study different facets of skin cell biology such as proliferation, apoptosis, migration and differentiation as well as epithelial-mesenchymal interactions, transitions and other cell-cell interactions.

In-vitro angiogenesis models (using endothelial cell culture and smooth muscle cell culture)

Monolayer (2-D) endothelial cell culture

3-D primary cell culture (endothelial cell-populated collagen lattices or Matrigel assay to study endothelial cell differentiation)

Monolayer co-culture (for direct cell-cell interaction studies)

Double-chamber co-culture (with smooth muscle cells or other cells for paracrine interaction studies)

Vascularised organotypic co-culture model (to study endothelial cell-fibroblast-keratinocyte interactions)

Organ culture (Nicosia’s technique)

Applications: These models can be used to study endothelial cell and angiogenetic biology, specifically proliferation, apoptosis, migration and differentiation as well as intercellular interactions and transitions.